2009
New Grants For Professor Edward Johns
Professor Edward Johns has received two major funding awards
Professor Edward Johns has received two major funding awards to support projects in the Renal Research Laboratory in the Department of Physiology. The first was and SFI Research Frontiers Programme grant which is to investigate the contribution of the angiotensin 1-7/ACE2 system in the regulation of renal haemodynamic and excretory function in models of hypertension. Knowledge of this system is sparse but the proposed research could open up avenues for translation into novel therapeutic development. The second award form the Wellcome Trust will investigate the contribution of brain angiotensin type 2 receptors (AT2R) in the reflex control of renal sympathetic nerve activity. There is evidence that activation of these receptors result in the generation of nitric oxide which may be a key mediator of AT2R activation and determine neuronal activity within the autonomic control centres of the brain.